BDBM152636 (2E)-1-(4-methoxyphenyl)-3-[2-(trifluoromethyl)phenyl]prop-2-en-1-one (M4)

SMILES: COc1ccc(cc1)C(=O)\C=C\c1ccccc1C(F)(F)F

InChI Key: InChIKey=IUJWAWAODSXWTI-DHZHZOJOSA-N

Data: 2 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 152636   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM152636 ((2E)-1-(4-methoxyphenyl)-3-[2-(trifluoromethyl)phe...) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccccc1C(F)(F)F Show InChI InChI=1S/C17H13F3O2/c1-22-14-9-6-13(7-10-14)16(21)11-8-12-4-2-3-5-15(12)17(18,19)20/h2-11H,1H3/b11-8+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	360	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Grace College of Pharmacy					Assay Description Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...				Bioorg Chem 62: 22-29 (2015) Article DOI: 10.1016/j.bioorg.2015.07.001 BindingDB Entry DOI: 10.7270/Q20K2795
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM152636 ((2E)-1-(4-methoxyphenyl)-3-[2-(trifluoromethyl)phe...) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccccc1C(F)(F)F Show InChI InChI=1S/C17H13F3O2/c1-22-14-9-6-13(7-10-14)16(21)11-8-12-4-2-3-5-15(12)17(18,19)20/h2-11H,1H3/b11-8+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Grace College of Pharmacy					Assay Description Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...				Bioorg Chem 62: 22-29 (2015) Article DOI: 10.1016/j.bioorg.2015.07.001 BindingDB Entry DOI: 10.7270/Q20K2795
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM152636 ((2E)-1-(4-methoxyphenyl)-3-[2-(trifluoromethyl)phe...) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccccc1C(F)(F)F Show InChI InChI=1S/C17H13F3O2/c1-22-14-9-6-13(7-10-14)16(21)11-8-12-4-2-3-5-15(12)17(18,19)20/h2-11H,1H3/b11-8+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human MAOA using p-tyramine as substrate after 30 mins by Amplex red based spectrophotometric analysis				Bioorg Med Chem 23: 6486-96 (2015) BindingDB Entry DOI: 10.7270/Q2MK6FPP
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM152636 ((2E)-1-(4-methoxyphenyl)-3-[2-(trifluoromethyl)phe...) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccccc1C(F)(F)F Show InChI InChI=1S/C17H13F3O2/c1-22-14-9-6-13(7-10-14)16(21)11-8-12-4-2-3-5-15(12)17(18,19)20/h2-11H,1H3/b11-8+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human MAOB using benzylamine as substrate after 30 mins by Amplex red based spectrophotometric analysis				Bioorg Med Chem 23: 6486-96 (2015) BindingDB Entry DOI: 10.7270/Q2MK6FPP
					More data for this Ligand-Target Pair