BDBM152728 5-Amino-N-hydroxypentanamide (4)

SMILES: [NH3+]CCCCC(=O)NO

InChI Key: InChIKey=YEOWNCJWBHIJNK-UHFFFAOYSA-O

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152728   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM152728 (5-Amino-N-hydroxypentanamide (4)) Show SMILES [NH3+]CCCCC(=O)NO Show InChI InChI=1S/C5H12N2O2/c6-4-2-1-3-5(8)7-9/h9H,1-4,6H2,(H,7,8)/p+1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	8.2	n/a
University of Pennsylvania					Assay Description Activity assays were conducted at 25 °C and contained 500 nM HDAC8 enzyme, 150 μM Ac-Arg-His-Lys(Ac)-Lys(Ac)-aminomethylcoumarin substrate (BML-...				Biochemistry 54: 4692-703 (2015) Article DOI: 10.1021/acs.biochem.5b00536 BindingDB Entry DOI: 10.7270/Q2FN14ZS
					More data for this Ligand-Target Pair
Acetylpolyamine amidohydrolase (APAH) (Mycoplana ramosa (Gram-negative bacterium))	BDBM152728 (5-Amino-N-hydroxypentanamide (4)) Show SMILES [NH3+]CCCCC(=O)NO Show InChI InChI=1S/C5H12N2O2/c6-4-2-1-3-5(8)7-9/h9H,1-4,6H2,(H,7,8)/p+1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	8.2	n/a
University of Pennsylvania					Assay Description Activity assays were conducted at 25 °C and contained 250 nM APAH (∼50% Zn2+ occupancy), 150 μM substrate, and 0−250 μM inhibit...				Biochemistry 54: 4692-703 (2015) Article DOI: 10.1021/acs.biochem.5b00536 BindingDB Entry DOI: 10.7270/Q2FN14ZS
					More data for this Ligand-Target Pair