BDBM152770 4-(3-Morpholinopropoxy)-N-(3-chlorophenyl)-2-hydroxybenzamide (9a)

SMILES: Oc1cc(OCCCN2CCOCC2)ccc1C(=O)Nc1cccc(Cl)c1

InChI Key: InChIKey=MOHICSQIFBMWEE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152770   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EGFR (Homo sapiens (Human))	BDBM152770 (4-(3-Morpholinopropoxy)-N-(3-chlorophenyl)-2-hydro...) Show SMILES Oc1cc(OCCCN2CCOCC2)ccc1C(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C20H23ClN2O4/c21-15-3-1-4-16(13-15)22-20(25)18-6-5-17(14-19(18)24)27-10-2-7-23-8-11-26-12-9-23/h1,3-6,13-14,24H,2,7-12H2,(H,22,25)	PDB MMDB B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	196	n/a	n/a	n/a	n/a	n/a	25
Anhui University of Chinese Medicine					Assay Description The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen...				Chem Biol Drug Des 85: 280-9 (2015) Article DOI: 10.1111/cbdd.12383 BindingDB Entry DOI: 10.7270/Q2JD4VJR
					More data for this Ligand-Target Pair