BDBM152774 4-(3-Morpholinopropoxy)-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide (13a)
SMILES: Oc1cc(OCCCN2CCOCC2)ccc1C(=O)Nc1ccc(cc1Cl)[N+]([O-])=O
InChI Key: InChIKey=JSFQEYLHQKILJI-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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EGFR (Homo sapiens (Human)) | BDBM152774 (4-(3-Morpholinopropoxy)-N-(2-chloro-4-nitrophenyl)...) | PDB MMDB B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 84.8 | n/a | n/a | n/a | n/a | n/a | 25 |
Anhui University of Chinese Medicine | Assay Description The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen... | Chem Biol Drug Des 85: 280-9 (2015) Article DOI: 10.1111/cbdd.12383 BindingDB Entry DOI: 10.7270/Q2JD4VJR | |||||||||||
More data for this Ligand-Target Pair |