BDBM15909 2-pyridinecarboxamide deriv. 3::4-Amino-5-cyano-6-ethoxy-pyridine-2-carboxylic acid 2,5-dimethoxy-benzylamide::4-amino-5-cyano-N-[(2,5-dimethoxyphenyl)methyl]-6-ethoxypyridine-2-carboxamide

SMILES: CCOc1nc(cc(N)c1C#N)C(=O)NCc1cc(OC)ccc1OC

InChI Key: InChIKey=OYPFBHGNPRGZHS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15909   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM15909 (2-pyridinecarboxamide deriv. 3 | 4-Amino-5-cyano-6...) Show SMILES CCOc1nc(cc(N)c1C#N)C(=O)NCc1cc(OC)ccc1OC Show InChI InChI=1S/C18H20N4O4/c1-4-26-18-13(9-19)14(20)8-15(22-18)17(23)21-10-11-7-12(24-2)5-6-16(11)25-3/h5-8H,4,10H2,1-3H3,(H2,20,22)(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...				J Med Chem 49: 4455-8 (2006) Article DOI: 10.1021/jm060465l BindingDB Entry DOI: 10.7270/Q2ST7N3W
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM15909 (2-pyridinecarboxamide deriv. 3 | 4-Amino-5-cyano-6...) Show SMILES CCOc1nc(cc(N)c1C#N)C(=O)NCc1cc(OC)ccc1OC Show InChI InChI=1S/C18H20N4O4/c1-4-26-18-13(9-19)14(20)8-15(22-18)17(23)21-10-11-7-12(24-2)5-6-16(11)25-3/h5-8H,4,10H2,1-3H3,(H2,20,22)(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	7.2	20
Abbott Laboratories					Assay Description In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...				J Med Chem 49: 4455-8 (2006) Article DOI: 10.1021/jm060465l BindingDB Entry DOI: 10.7270/Q2ST7N3W
					More data for this Ligand-Target Pair