BDBM15920 2-pyridinecarboxamide deriv. 15::4-Amino-6-chloro-5-cyano-pyridine-2-carboxylic acid 4-methanesulfonyl-benzylamide::4-amino-6-chloro-5-cyano-N-[(4-methanesulfonylphenyl)methyl]pyridine-2-carboxamide

SMILES: CS(=O)(=O)c1ccc(CNC(=O)c2cc(N)c(C#N)c(Cl)n2)cc1

InChI Key: InChIKey=AHBMLIVZIANQGH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15920   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM15920 (2-pyridinecarboxamide deriv. 15 | 4-Amino-6-chloro...) Show SMILES CS(=O)(=O)c1ccc(CNC(=O)c2cc(N)c(C#N)c(Cl)n2)cc1 Show InChI InChI=1S/C15H13ClN4O3S/c1-24(22,23)10-4-2-9(3-5-10)8-19-15(21)13-6-12(18)11(7-17)14(16)20-13/h2-6H,8H2,1H3,(H2,18,20)(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...				J Med Chem 49: 4455-8 (2006) Article DOI: 10.1021/jm060465l BindingDB Entry DOI: 10.7270/Q2ST7N3W
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM15920 (2-pyridinecarboxamide deriv. 15 | 4-Amino-6-chloro...) Show SMILES CS(=O)(=O)c1ccc(CNC(=O)c2cc(N)c(C#N)c(Cl)n2)cc1 Show InChI InChI=1S/C15H13ClN4O3S/c1-24(22,23)10-4-2-9(3-5-10)8-19-15(21)13-6-12(18)11(7-17)14(16)20-13/h2-6H,8H2,1H3,(H2,18,20)(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	7.2	20
Abbott Laboratories					Assay Description In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...				J Med Chem 49: 4455-8 (2006) Article DOI: 10.1021/jm060465l BindingDB Entry DOI: 10.7270/Q2ST7N3W
					More data for this Ligand-Target Pair