BDBM15921 2-pyridinecarboxamide deriv. 17a::5-Cyano-6-ethoxy-pyridine-2-carboxylic acid 4-methanesulfonyl-benzylamide::5-cyano-6-ethoxy-N-[(4-methanesulfonylphenyl)methyl]pyridine-2-carboxamide

SMILES: CCOc1nc(ccc1C#N)C(=O)NCc1ccc(cc1)S(C)(=O)=O

InChI Key: InChIKey=GCJDFBAXDJMMIC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15921   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM15921 (2-pyridinecarboxamide deriv. 17a | 5-Cyano-6-ethox...) Show SMILES CCOc1nc(ccc1C#N)C(=O)NCc1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C17H17N3O4S/c1-3-24-17-13(10-18)6-9-15(20-17)16(21)19-11-12-4-7-14(8-5-12)25(2,22)23/h4-9H,3,11H2,1-2H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	7.2	20
Abbott Laboratories					Assay Description In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...				J Med Chem 49: 4455-8 (2006) Article DOI: 10.1021/jm060465l BindingDB Entry DOI: 10.7270/Q2ST7N3W
					More data for this Ligand-Target Pair