BDBM161162 US9682976, 48

SMILES: Cn1nnn(-c2cc(Nc3ncc(F)c(N[C@@H]4C[C@@H]5CCCN5C(C)(C)C4)n3)ccc2O[C@@H]2CCOC2)c1=O

InChI Key: InChIKey=LDUSGAYKQIOKIX-CEXWTWQISA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161162   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 (IL-2) (Homo sapiens (Human))	BDBM161162 (US9682976, 48) Show SMILES Cn1nnn(-c2cc(Nc3ncc(F)c(N[C@@H]4C[C@@H]5CCCN5C(C)(C)C4)n3)ccc2O[C@@H]2CCOC2)c1=O |r| Show InChI InChI=1S/C26H34FN9O3/c1-26(2)13-17(11-18-5-4-9-35(18)26)29-23-20(27)14-28-24(31-23)30-16-6-7-22(39-19-8-10-38-15-19)21(12-16)36-25(37)34(3)32-33-36/h6-7,12,14,17-19H,4-5,8-11,13,15H2,1-3H3,(H2,28,29,30,31)/t17-,18+,19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Primary T cell stimulation and IL2 ELISA: Human primary T cells (100,000 cells per well) were pre-incubated with or without test compound in Yssel...				US Patent US9682976 (2017) BindingDB Entry DOI: 10.7270/Q2DJ5CT2
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