BDBM161805 US9682976, 242

SMILES: COc1cc(cc(Nc2ncc(F)c(N[C@@H]3C[C@@H]4CCCN4C(C)(C)C3)n2)c1F)-n1nnnc1C

InChI Key: InChIKey=ISCXKFXOPIJVFT-CABCVRRESA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161805   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 (IL-2) (Homo sapiens (Human))	BDBM161805 (US9682976, 242) Show SMILES COc1cc(cc(Nc2ncc(F)c(N[C@@H]3C[C@@H]4CCCN4C(C)(C)C3)n2)c1F)-n1nnnc1C |r| Show InChI InChI=1S/C23H29F2N9O/c1-13-30-31-32-34(13)16-9-18(20(25)19(10-16)35-4)28-22-26-12-17(24)21(29-22)27-14-8-15-6-5-7-33(15)23(2,3)11-14/h9-10,12,14-15H,5-8,11H2,1-4H3,(H2,26,27,28,29)/t14-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Primary T cell stimulation and IL2 ELISA: Human primary T cells (100,000 cells per well) were pre-incubated with or without test compound in Yssel...				US Patent US9682976 (2017) BindingDB Entry DOI: 10.7270/Q2DJ5CT2
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