BDBM16309 2-(quinolin-8-yl)-1H-1,3-benzodiazole-6-carboximidamide::2-quinolin-8-yl-1H-benzimidazole-6-carboximidamide::APD-7

SMILES: NC(=N)c1ccc2nc([nH]c2c1)-c1cccc2cccnc12

InChI Key: InChIKey=QFXZSLFLWAJDDV-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 16309   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM16309 (2-(quinolin-8-yl)-1H-1,3-benzodiazole-6-carboximid...) Show SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1cccc2cccnc12 Show InChI InChI=1S/C17H13N5/c18-16(19)11-6-7-13-14(9-11)22-17(21-13)12-5-1-3-10-4-2-8-20-15(10)12/h1-9H,(H3,18,19)(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	321	-8.76	n/a	n/a	n/a	n/a	n/a	8.2	22
Arris					Assay Description Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...				Nature 391: 608-12 (1998) Article DOI: 10.1038/35422 BindingDB Entry DOI: 10.7270/Q29P2ZW9
					More data for this Ligand-Target Pair
Trypsin-1 (Homo sapiens (Human))	BDBM16309 (2-(quinolin-8-yl)-1H-1,3-benzodiazole-6-carboximid...) Show SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1cccc2cccnc12 Show InChI InChI=1S/C17H13N5/c18-16(19)11-6-7-13-14(9-11)22-17(21-13)12-5-1-3-10-4-2-8-20-15(10)12/h1-9H,(H3,18,19)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	8.04E+3	-6.88	n/a	n/a	n/a	n/a	n/a	8.2	22
Arris					Assay Description Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...				Nature 391: 608-12 (1998) Article DOI: 10.1038/35422 BindingDB Entry DOI: 10.7270/Q29P2ZW9
					More data for this Ligand-Target Pair
Tryptase (Homo sapiens (Human))	BDBM16309 (2-(quinolin-8-yl)-1H-1,3-benzodiazole-6-carboximid...) Show SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1cccc2cccnc12 Show InChI InChI=1S/C17H13N5/c18-16(19)11-6-7-13-14(9-11)22-17(21-13)12-5-1-3-10-4-2-8-20-15(10)12/h1-9H,(H3,18,19)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	1.10E+4	-6.69	n/a	n/a	n/a	n/a	n/a	8.2	22
Arris					Assay Description Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...				Nature 391: 608-12 (1998) Article DOI: 10.1038/35422 BindingDB Entry DOI: 10.7270/Q29P2ZW9
					More data for this Ligand-Target Pair
Tryptase (Homo sapiens (Human))	BDBM16309 (2-(quinolin-8-yl)-1H-1,3-benzodiazole-6-carboximid...) Show SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1cccc2cccnc12 Show InChI InChI=1S/C17H13N5/c18-16(19)11-6-7-13-14(9-11)22-17(21-13)12-5-1-3-10-4-2-8-20-15(10)12/h1-9H,(H3,18,19)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arris					Assay Description Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...				Nature 391: 608-12 (1998) Article DOI: 10.1038/35422 BindingDB Entry DOI: 10.7270/Q29P2ZW9
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM16309 (2-(quinolin-8-yl)-1H-1,3-benzodiazole-6-carboximid...) Show SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1cccc2cccnc12 Show InChI InChI=1S/C17H13N5/c18-16(19)11-6-7-13-14(9-11)22-17(21-13)12-5-1-3-10-4-2-8-20-15(10)12/h1-9H,(H3,18,19)(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	2.01E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arris					Assay Description Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...				Nature 391: 608-12 (1998) Article DOI: 10.1038/35422 BindingDB Entry DOI: 10.7270/Q29P2ZW9
					More data for this Ligand-Target Pair
Trypsin-1 (Homo sapiens (Human))	BDBM16309 (2-(quinolin-8-yl)-1H-1,3-benzodiazole-6-carboximid...) Show SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1cccc2cccnc12 Show InChI InChI=1S/C17H13N5/c18-16(19)11-6-7-13-14(9-11)22-17(21-13)12-5-1-3-10-4-2-8-20-15(10)12/h1-9H,(H3,18,19)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	4.18E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arris					Assay Description Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...				Nature 391: 608-12 (1998) Article DOI: 10.1038/35422 BindingDB Entry DOI: 10.7270/Q29P2ZW9
					More data for this Ligand-Target Pair