BDBM165919 US9067924, 13

SMILES: NC1=NC(CCS(=O)(=O)C1)(C(F)F)c1cc(NC(=O)c2ccc(cn2)[N+]#[C-])ccc1F

InChI Key: InChIKey=CIEGCRCCBXUZRY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 165919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (BACE1) (Mus musculus (Mouse))	BDBM165919 (US9067924, 13) Show SMILES NC1=NC(CCS(=O)(=O)C1)(C(F)F)c1cc(NC(=O)c2ccc(cn2)[N+]#[C-])ccc1F |t:1| Show InChI InChI=1S/C19H16F3N5O3S/c1-24-12-3-5-15(25-9-12)17(28)26-11-2-4-14(20)13(8-11)19(18(21)22)6-7-31(29,30)10-16(23)27-19/h2-5,8-9,18H,6-7,10H2,(H2,23,27)(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description An ELISA assay (using a pair of mouse anti-human-TMEM27 antibodies, raised against the extracellular domain of TMEM27) is used for detection of TMEM2...				US Patent US9067924 (2015) BindingDB Entry DOI: 10.7270/Q2R21049
					More data for this Ligand-Target Pair