BDBM170561 US9085549, 72
SMILES: Oc1ccc(cc1O)-c1nnc(s1)-c1ccc(O)c(O)c1
InChI Key: InChIKey=SQQUCACGXUDDAS-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-synuclein (Homo sapiens (Human)) | BDBM170561 (US9085549, 72) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 270 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
PROTEOTECH INC US Patent | Assay Description The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h... | US Patent US9085549 (2015) BindingDB Entry DOI: 10.7270/Q2WD3Z9K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tau (Homo sapiens (Human)) | BDBM170561 (US9085549, 72) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
PROTEOTECH INC US Patent | Assay Description The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated... | US Patent US9085549 (2015) BindingDB Entry DOI: 10.7270/Q2WD3Z9K | |||||||||||
More data for this Ligand-Target Pair |