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BDBM172584 US9675593, 650

SMILES: FC(F)(F)Oc1ccc(cc1)-n1cc(-c2cn[nH]c2)c2ccn(C3CC3)c2c1=O

InChI Key: InChIKey=UVHKJOBRHCKXIV-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 172584   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Endothelin-1


(Homo sapiens (Human))
BDBM172584
PNG
(US9675593, 650)
Show SMILES FC(F)(F)Oc1ccc(cc1)-n1cc(-c2cn[nH]c2)c2ccn(C3CC3)c2c1=O
Show InChI InChI=1S/C20H15F3N4O2/c21-20(22,23)29-15-5-3-14(4-6-15)27-11-17(12-9-24-25-10-12)16-7-8-26(13-1-2-13)18(16)19(27)28/h3-11,13H,1-2H2,(H,24,25)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<5.00E+4n/an/an/an/a



SRMLSC

US Patent


Assay Description
Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...


US Patent US9675593 (2017)


BindingDB Entry DOI: 10.7270/Q2319T24
More data for this
Ligand-Target Pair