BDBM173152 US9096589, (S)-1-{2-[2-(5-Methyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-ethyl]-4-thiophen-2-yl-imidazol-1-yl}-3-morpholin-4-yl-propan-2-ol

SMILES: Cc1cccc2nc(CCc3nc(cn3C[C@@H](O)CN3CCOCC3)-c3cccs3)nn12

InChI Key: InChIKey=DVNGANNMDBGMIS-SFHVURJKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173152   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM173152 (US9096589, (S)-1-{2-[2-(5-Methyl-[1,2,4]triazolo[1...) Show SMILES Cc1cccc2nc(CCc3nc(cn3C[C@@H](O)CN3CCOCC3)-c3cccs3)nn12 Show InChI InChI=1S/C23H28N6O2S/c1-17-4-2-6-23-25-21(26-29(17)23)7-8-22-24-19(20-5-3-13-32-20)16-28(22)15-18(30)14-27-9-11-31-12-10-27/h2-6,13,16,18,30H,7-12,14-15H2,1H3/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9096589 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TTM
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