Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM173152'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM173152 (US9096589, (S)-1-{2-[2-(5-Methyl-[1,2,4]triazolo[1...) Show SMILES Cc1cccc2nc(CCc3nc(cn3C[C@@H](O)CN3CCOCC3)-c3cccs3)nn12 Show InChI InChI=1S/C23H28N6O2S/c1-17-4-2-6-23-25-21(26-29(17)23)7-8-22-24-19(20-5-3-13-32-20)16-28(22)15-18(30)14-27-9-11-31-12-10-27/h2-6,13,16,18,30H,7-12,14-15H2,1H3/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9096589 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TTM
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