BDBM173566 1-(2-Oxo-2H-chromene-3-carbonyl)-3-(3-chlorophenyl)thiourea (2e)

SMILES: Clc1cccc(NC(=S)NC(=O)c2cc3ccccc3oc2=O)c1

InChI Key: InChIKey=GYLPAOQHWGETRB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM173566 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(3-chlorophenyl...) Show SMILES Clc1cccc(NC(=S)NC(=O)c2cc3ccccc3oc2=O)c1 Show InChI InChI=1S/C17H11ClN2O3S/c18-11-5-3-6-12(9-11)19-17(24)20-15(21)13-8-10-4-1-2-7-14(10)23-16(13)22/h1-9H,(H2,19,20,21,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-I-Azam University					Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ...				Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM173566 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(3-chlorophenyl...) Show SMILES Clc1cccc(NC(=S)NC(=O)c2cc3ccccc3oc2=O)c1 Show InChI InChI=1S/C17H11ClN2O3S/c18-11-5-3-6-12(9-11)19-17(24)20-15(21)13-8-10-4-1-2-7-14(10)23-16(13)22/h1-9H,(H2,19,20,21,24)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-I-Azam University					Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ...				Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4
					More data for this Ligand-Target Pair