BDBM173569 1-(2-Oxo-2H-chromene-3-carbonyl)-3-(2,4-dichlorophenyl)thiourea (2h)

SMILES: Clc1ccc(NC(=S)NC(=O)c2cc3ccccc3oc2=O)c(Cl)c1

InChI Key: InChIKey=SEOXZAHNNRNNLY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173569   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM173569 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(2,4-dichloroph...) Show SMILES Clc1ccc(NC(=S)NC(=O)c2cc3ccccc3oc2=O)c(Cl)c1 Show InChI InChI=1S/C17H10Cl2N2O3S/c18-10-5-6-13(12(19)8-10)20-17(25)21-15(22)11-7-9-3-1-2-4-14(9)24-16(11)23/h1-8H,(H2,20,21,22,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-I-Azam University					Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ...				Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM173569 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(2,4-dichloroph...) Show SMILES Clc1ccc(NC(=S)NC(=O)c2cc3ccccc3oc2=O)c(Cl)c1 Show InChI InChI=1S/C17H10Cl2N2O3S/c18-10-5-6-13(12(19)8-10)20-17(25)21-15(22)11-7-9-3-1-2-4-14(9)24-16(11)23/h1-8H,(H2,20,21,22,25)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-I-Azam University					Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ...				Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4
					More data for this Ligand-Target Pair