BDBM173585 (2E)-1-(3-hydroxynaphthalen-2-yl)-3-(2-hydroxy-4-nitrophenyl) prop-2-en-1-one (3b)

SMILES: Oc1cc(ccc1\C=C\C(=O)c1cc2ccccc2cc1O)[N+]([O-])=O

InChI Key: InChIKey=FGMFHNAISMFJAN-SOFGYWHQSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173585   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L] (Agaricus bisporus (Mushroom))	BDBM173585 ((2E)-1-(3-hydroxynaphthalen-2-yl)-3-(2-hydroxy-4-n...) Show SMILES Oc1cc(ccc1\C=C\C(=O)c1cc2ccccc2cc1O)[N+]([O-])=O Show InChI InChI=1S/C19H13NO5/c21-17(8-6-12-5-7-15(20(24)25)11-18(12)22)16-9-13-3-1-2-4-14(13)10-19(16)23/h1-11,22-23H/b8-6+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.12E+4	n/a	2.29E+4	n/a	n/a	n/a	n/a	6.8	n/a
University of Technology Sydney					Assay Description The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...				Bioorg Chem 63: 116-22 (2015) Article DOI: 10.1016/j.bioorg.2015.10.003 BindingDB Entry DOI: 10.7270/Q2MS3RH3
					More data for this Ligand-Target Pair