BDBM17375 1,2,4-Triazole Compound, 33::5-{[(5-methyl-1,2-oxazol-3-yl)methyl]sulfanyl}-N-(4-methylphenyl)-4H-1,2,4-triazol-3-amine

SMILES: Cc1cc(CSc2nnc(Nc3ccc(C)cc3)[nH]2)no1

InChI Key: InChIKey=QWHUCUJGEQGJHL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17375 (1,2,4-Triazole Compound, 33 | 5-{[(5-methyl-1,2-ox...) Show SMILES Cc1cc(CSc2nnc(Nc3ccc(C)cc3)[nH]2)no1 Show InChI InChI=1S/C14H15N5OS/c1-9-3-5-11(6-4-9)15-13-16-14(18-17-13)21-8-12-7-10(2)20-19-12/h3-7H,8H2,1-2H3,(H2,15,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 50: 3777-85 (2007) Article DOI: 10.1021/jm061182w BindingDB Entry DOI: 10.7270/Q2B856D7
					More data for this Ligand-Target Pair