BDBM176194 US10047103, 227::US9688695, 227

SMILES: COc1cc(OCc2nc(sc2C)-c2ccnc(F)c2)c2cc(oc2c1)-c1cn2nc(C)ccc2n1

InChI Key: InChIKey=WYIXGZUDGCSVKP-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 176194   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 4 (PAR4) (Homo sapiens (Human))	BDBM176194 (US10047103, 227 | US9688695, 227) Show SMILES COc1cc(OCc2nc(sc2C)-c2ccnc(F)c2)c2cc(oc2c1)-c1cn2nc(C)ccc2n1 Show InChI InChI=1S/C26H20FN5O3S/c1-14-4-5-25-29-19(12-32(25)31-14)23-11-18-21(9-17(33-3)10-22(18)35-23)34-13-20-15(2)36-26(30-20)16-6-7-28-24(27)8-16/h4-12H,13H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.310	n/a	n/a	n/a	25
Bristol-Myers Squibb Company; Universite de Montreal US Patent					Assay Description The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...				US Patent US10047103 (2018) BindingDB Entry DOI: 10.7270/Q2QF8VWN
					More data for this Ligand-Target Pair
Proteinase-activated receptor 4 (PAR4) (Homo sapiens (Human))	BDBM176194 (US10047103, 227 | US9688695, 227) Show SMILES COc1cc(OCc2nc(sc2C)-c2ccnc(F)c2)c2cc(oc2c1)-c1cn2nc(C)ccc2n1 Show InChI InChI=1S/C26H20FN5O3S/c1-14-4-5-25-29-19(12-32(25)31-14)23-11-18-21(9-17(33-3)10-22(18)35-23)34-13-20-15(2)36-26(30-20)16-6-7-28-24(27)8-16/h4-12H,13H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.310	n/a	n/a	n/a	25
BRISTOL-MYERS SQUIBB COMPANY US Patent					Assay Description Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...				US Patent US9688695 (2017) BindingDB Entry DOI: 10.7270/Q28K777N
					More data for this Ligand-Target Pair