BDBM176350 US9688696, 66

SMILES: CC(C)n1ncc2nc([nH]c12)-c1ccc(cc1)N1CCN(CC1)C(=O)Nc1ccccc1C(F)(F)F

InChI Key: InChIKey=BXLXGHUSGODYHQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM176350 (US9688696, 66) Show SMILES CC(C)n1ncc2nc([nH]c12)-c1ccc(cc1)N1CCN(CC1)C(=O)Nc1ccccc1C(F)(F)F Show InChI InChI=1S/C25H26F3N7O/c1-16(2)35-23-21(15-29-35)30-22(32-23)17-7-9-18(10-8-17)33-11-13-34(14-12-33)24(36)31-20-6-4-3-5-19(20)25(26,27)28/h3-10,15-16H,11-14H2,1-2H3,(H,30,32)(H,31,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	79	n/a	n/a	n/a	n/a	7.4	25
Janssen Pharmaceutica N.V. US Patent					Assay Description DGAT activity in membrane preparations was assayed in 50 mM Tris-HCl (pH 7.4), 150 mM MgCl2, 1 mM EDTA and 0.2% BSA, containing 50 μM DAG, 32 &#...				US Patent US9688696 (2017) BindingDB Entry DOI: 10.7270/Q24X55ZP
					More data for this Ligand-Target Pair