BDBM178010 2-(3-((2,3-difluorobenzyl)oxy)phenyl)-4H-chromen-4-one (13)

SMILES: Fc1cccc(COc2cccc(c2)-c2cc(=O)c3ccccc3o2)c1F

InChI Key: InChIKey=MSFFBKIIQUFELX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 178010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
α-glucosidase (Saccharomyces cerevisiae S288c (Baker's yeast))	BDBM178010 (2-(3-((2,3-difluorobenzyl)oxy)phenyl)-4H-chromen-4...) Show SMILES Fc1cccc(COc2cccc(c2)-c2cc(=O)c3ccccc3o2)c1F Show InChI InChI=1S/C22H14F2O3/c23-18-9-4-6-15(22(18)24)13-26-16-7-3-5-14(11-16)21-12-19(25)17-8-1-2-10-20(17)27-21/h1-12H,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.49E+3	n/a	n/a	n/a	n/a	6.8	n/a
Universiti Teknologi MARA					Assay Description The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...				Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS
					More data for this Ligand-Target Pair