BDBM17852 3-octanamido-N-(1,3-thiazol-2-yl)pyridine-2-carboxamide::pyridine-2-carboxylic acid inhibitor, 5

SMILES: CCCCCCCC(=O)Nc1cccnc1C(=O)Nc1nccs1

InChI Key: InChIKey=OMZPJYPOZOMBFT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17852   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17852 (3-octanamido-N-(1,3-thiazol-2-yl)pyridine-2-carbox...) Show SMILES CCCCCCCC(=O)Nc1cccnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C17H22N4O2S/c1-2-3-4-5-6-9-14(22)20-13-8-7-10-18-15(13)16(23)21-17-19-11-12-24-17/h7-8,10-12H,2-6,9H2,1H3,(H,20,22)(H,19,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	7.5	22
Johns Hopkins University					Assay Description The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...				Proc Natl Acad Sci U S A 103: 18148-53 (2006) Article DOI: 10.1073/pnas.0608389103 BindingDB Entry DOI: 10.7270/Q2RB72VK
					More data for this Ligand-Target Pair
Methionine Aminopeptidase Type 1 (MetAP1) (Homo sapiens (Human))	BDBM17852 (3-octanamido-N-(1,3-thiazol-2-yl)pyridine-2-carbox...) Show SMILES CCCCCCCC(=O)Nc1cccnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C17H22N4O2S/c1-2-3-4-5-6-9-14(22)20-13-8-7-10-18-15(13)16(23)21-17-19-11-12-24-17/h7-8,10-12H,2-6,9H2,1H3,(H,20,22)(H,19,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	7.5	22
Johns Hopkins University					Assay Description The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...				Proc Natl Acad Sci U S A 103: 18148-53 (2006) Article DOI: 10.1073/pnas.0608389103 BindingDB Entry DOI: 10.7270/Q2RB72VK
					More data for this Ligand-Target Pair