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BDBM18609 6-[bis(2,2,2-trifluoroethyl)amino]-4-hydroxy-1,2-dihydroquinolin-2-one::6-bisalkylamino-2-quinolinone, 7j

SMILES: Oc1cc(=O)[nH]c2ccc(cc12)N(CC(F)(F)F)CC(F)(F)F

InChI Key: InChIKey=SMMFLUXSBYESHE-UHFFFAOYSA-N

Data: 1 KI  1 IC50  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18609   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Androgen Receptor


(Homo sapiens (Human))
BDBM18609
PNG
(6-[bis(2,2,2-trifluoroethyl)amino]-4-hydroxy-1,2-d...)
Show SMILES Oc1cc(=O)[nH]c2ccc(cc12)N(CC(F)(F)F)CC(F)(F)F
Show InChI InChI=1S/C13H10F6N2O2/c14-12(15,16)5-21(6-13(17,18)19)7-1-2-9-8(3-7)10(22)4-11(23)20-9/h1-4H,5-6H2,(H2,20,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
1.00E+3n/a 7n/a 83n/an/an/an/a



Ligand Pharmaceuticals Inc.



Assay Description
The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...


Bioorg Med Chem Lett 17: 1527-31 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.001
BindingDB Entry DOI: 10.7270/Q2XS5SP9
More data for this
Ligand-Target Pair