BDBM189344 (3-Chlorophenyl)(4-methylpiperazin-1-yl)methanone (2)
SMILES: CN1CCN(CC1)C(=O)c1cccc(Cl)c1
InChI Key: InChIKey=JMCVROBSFMMHPI-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H4 receptor (Homo sapiens (Human)) | BDBM189344 ((3-Chlorophenyl)(4-methylpiperazin-1-yl)methanone ...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 3.88E+3 | -6.86 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Jagiellonian University Medical College | Assay Description Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12... | Chem Biol Drug Des 88: 254-63 (2016) Article DOI: 10.1111/cbdd.12752 BindingDB Entry DOI: 10.7270/Q21R6P93 | |||||||||||
More data for this Ligand-Target Pair |