BDBM189388 3-((1-(4-ethylphenyl)-1H-1,2,3-triazol-4-yl)methyl)oxazolo[4,5-b]pyridin-2(3H)-one (4h)

SMILES: CCc1ccc(cc1)-n1cc(Cn2c3ncccc3oc2=O)nn1

InChI Key: InChIKey=DFARZBBHARIVCI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 189388   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM189388 (3-((1-(4-ethylphenyl)-1H-1,2,3-triazol-4-yl)methyl...) Show SMILES CCc1ccc(cc1)-n1cc(Cn2c3ncccc3oc2=O)nn1 Show InChI InChI=1S/C17H15N5O2/c1-2-12-5-7-14(8-6-12)22-11-13(19-20-22)10-21-16-15(24-17(21)23)4-3-9-18-16/h3-9,11H,2,10H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.27E+4	n/a	n/a	n/a	n/a	n/a	30
Hamdard University (Jamia Hamdard)					Assay Description In a typical assay, 10 µL of test compound of different concentrations (dissolvedin dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 µ...				Chem Biol Drug Des 87: 918-26 (2016) Article DOI: 10.1111/cbdd.12724 BindingDB Entry DOI: 10.7270/Q28914NR
					More data for this Ligand-Target Pair