BDBM189390 3-((1-(3,4-dimethylphenyl)-1H-1,2,3-triazol-4-yl)methyl)oxazolo[4,5-b]pyridin-3H)one (4j)

SMILES: Cc1ccc(cc1C)-n1cc(Cn2c3ncccc3oc2=O)nn1

InChI Key: InChIKey=OZCMBSJGTOZESG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 189390   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM189390 (3-((1-(3,4-dimethylphenyl)-1H-1,2,3-triazol-4-yl)m...) Show SMILES Cc1ccc(cc1C)-n1cc(Cn2c3ncccc3oc2=O)nn1 Show InChI InChI=1S/C17H15N5O2/c1-11-5-6-14(8-12(11)2)22-10-13(19-20-22)9-21-16-15(24-17(21)23)4-3-7-18-16/h3-8,10H,9H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.01E+4	n/a	n/a	n/a	n/a	n/a	30
Hamdard University (Jamia Hamdard)					Assay Description In a typical assay, 10 µL of test compound of different concentrations (dissolvedin dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 µ...				Chem Biol Drug Des 87: 918-26 (2016) Article DOI: 10.1111/cbdd.12724 BindingDB Entry DOI: 10.7270/Q28914NR
					More data for this Ligand-Target Pair