BDBM199192 7-Chloro-N-(2-methoxybenzyl)-1,2,3,4-tetrahydroacridin-9-amine (10b)

SMILES: COc1ccccc1CNc1c2CCCCc2nc2ccc(Cl)cc12

InChI Key: InChIKey=JQCUHQZFFVRUOS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 199192   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Homo sapiens (Human))	BDBM199192 (7-Chloro-N-(2-methoxybenzyl)-1,2,3,4-tetrahydroacr...) Show SMILES COc1ccccc1CNc1c2CCCCc2nc2ccc(Cl)cc12 Show InChI InChI=1S/C21H21ClN2O/c1-25-20-9-5-2-6-14(20)13-23-21-16-7-3-4-8-18(16)24-19-11-10-15(22)12-17(19)21/h2,5-6,9-12H,3-4,7-8,13H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	8.0	25
University of Waterloo					Assay Description Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...				Chem Biol Drug Des 88: 710-723 (2016) Article DOI: 10.1111/cbdd.12800 BindingDB Entry DOI: 10.7270/Q26D5RSX
					More data for this Ligand-Target Pair
Cholinesterases (Homo sapiens (Human))	BDBM199192 (7-Chloro-N-(2-methoxybenzyl)-1,2,3,4-tetrahydroacr...) Show SMILES COc1ccccc1CNc1c2CCCCc2nc2ccc(Cl)cc12 Show InChI InChI=1S/C21H21ClN2O/c1-25-20-9-5-2-6-14(20)13-23-21-16-7-3-4-8-18(16)24-19-11-10-15(22)12-17(19)21/h2,5-6,9-12H,3-4,7-8,13H2,1H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	8.0	25
University of Waterloo					Assay Description Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...				Chem Biol Drug Des 88: 710-723 (2016) Article DOI: 10.1111/cbdd.12800 BindingDB Entry DOI: 10.7270/Q26D5RSX
					More data for this Ligand-Target Pair