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BDBM201057 US9233953, 18

SMILES: Fc1cccc(C2CN(CCN2C(=O)C2CCS(=O)(=O)CC2)c2cc(on2)C(F)(F)F)c1F

InChI Key: InChIKey=YTLUKWXDWZGNJB-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 201057   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM201057
PNG
(US9233953, 18)
Show SMILES Fc1cccc(C2CN(CCN2C(=O)C2CCS(=O)(=O)CC2)c2cc(on2)C(F)(F)F)c1F
Show InChI InChI=1/C20H20F5N3O4S/c21-14-3-1-2-13(18(14)22)15-11-27(17-10-16(32-26-17)20(23,24)25)6-7-28(15)19(29)12-4-8-33(30,31)9-5-12/h1-3,10,12,15H,4-9,11H2
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Cells expressing either endogenously the GlyT1 transporter like JAR cells (human placental choriocarcinoma cells; e.g. WO 2008/002583) or SK-N-MC cel...


US Patent US9233953 (2016)


BindingDB Entry DOI: 10.7270/Q2Q81BVM
More data for this
Ligand-Target Pair