BDBM202320 1-((4as,7ar)-6-(methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino)hexahydro-1h-cyclopenta[c]pyridin-2(3h,4h,4ah,5h,6h,7h,7ah)-yl)ethanone::US9527851, example 35

SMILES: CN(Cc1ccccc1)C1C[C@H]2CCN(C[C@H]2C1)C(=O)OC(C)(C)C

InChI Key: InChIKey=UFVUDSYXEFXWFK-PWCSWUJKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 202320   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM202320 (1-((4as,7ar)-6-(methyl(7h-pyrrolo[2,3-d]pyrimidin-...) Show SMILES CN(Cc1ccccc1)C1C[C@H]2CCN(C[C@H]2C1)C(=O)OC(C)(C)C |r| Show InChI InChI=1S/C21H32N2O2/c1-21(2,3)25-20(24)23-11-10-17-12-19(13-18(17)15-23)22(4)14-16-8-6-5-7-9-16/h5-9,17-19H,10-15H2,1-4H3/t17-,18-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.3	25
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent					Assay Description In vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK2 kinase. The test ...				US Patent US9527851 (2016) BindingDB Entry DOI: 10.7270/Q2D21VRM
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM202320 (1-((4as,7ar)-6-(methyl(7h-pyrrolo[2,3-d]pyrimidin-...) Show SMILES CN(Cc1ccccc1)C1C[C@H]2CCN(C[C@H]2C1)C(=O)OC(C)(C)C |r| Show InChI InChI=1S/C21H32N2O2/c1-21(2,3)25-20(24)23-11-10-17-12-19(13-18(17)15-23)22(4)14-16-8-6-5-7-9-16/h5-9,17-19H,10-15H2,1-4H3/t17-,18-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.3	25
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent					Assay Description TBDIn vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK1 kinase. The te...				US Patent US9527851 (2016) BindingDB Entry DOI: 10.7270/Q2D21VRM
					More data for this Ligand-Target Pair