Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM202320'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM202320 (1-((4as,7ar)-6-(methyl(7h-pyrrolo[2,3-d]pyrimidin-...) Show SMILES CN(Cc1ccccc1)C1C[C@H]2CCN(C[C@H]2C1)C(=O)OC(C)(C)C |r| Show InChI InChI=1S/C21H32N2O2/c1-21(2,3)25-20(24)23-11-10-17-12-19(13-18(17)15-23)22(4)14-16-8-6-5-7-9-16/h5-9,17-19H,10-15H2,1-4H3/t17-,18-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.3	25
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent					Assay Description TBDIn vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK1 kinase. The te...				US Patent US9527851 (2016) BindingDB Entry DOI: 10.7270/Q2D21VRM
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