BDBM20719 (1R,2R)-2-({4-[4-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)phenyl]phenyl}carbonyl)cyclopentane-1-carboxylic acid::Urea-based Analogue, 4c

SMILES: OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1

InChI Key: InChIKey=OMVIMIJGNZGGRI-DHIUTWEWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20719   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM20719 ((1R,2R)-2-({4-[4-({[3-(trifluoromethyl)phenyl]carb...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C27H23F3N2O4/c28-27(29,30)19-3-1-4-21(15-19)32-26(36)31-20-13-11-17(12-14-20)16-7-9-18(10-8-16)24(33)22-5-2-6-23(22)25(34)35/h1,3-4,7-15,22-23H,2,5-6H2,(H,34,35)(H2,31,32,36)/t22-,23-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM20719 ((1R,2R)-2-({4-[4-({[3-(trifluoromethyl)phenyl]carb...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C27H23F3N2O4/c28-27(29,30)19-3-1-4-21(15-19)32-26(36)31-20-13-11-17(12-14-20)16-7-9-18(10-8-16)24(33)22-5-2-6-23(22)25(34)35/h1,3-4,7-15,22-23H,2,5-6H2,(H,34,35)(H2,31,32,36)/t22-,23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair