BDBM210898 US9273043, A126(e)

SMILES: C[C@@H]1CN(CCN1C(=O)Nc1nc2ccc(C)cc2s1)c1ncc(cc1F)[C@@H](O)CO

InChI Key: InChIKey=MOYYIRTYGZTKTA-DYVFJYSZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 210898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM210898 (US9273043, A126(e)) Show SMILES C[C@@H]1CN(CCN1C(=O)Nc1nc2ccc(C)cc2s1)c1ncc(cc1F)[C@@H](O)CO |r| Show InChI InChI=1S/C21H24FN5O3S/c1-12-3-4-16-18(7-12)31-20(24-16)25-21(30)27-6-5-26(10-13(27)2)19-15(22)8-14(9-23-19)17(29)11-28/h3-4,7-9,13,17,28-29H,5-6,10-11H2,1-2H3,(H,24,25,30)/t13-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.2	37
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description pH dependent Ca2+ responses in TRPV1/CHO cells cultured in a 96-well plate were determined (see, e.g., FIG. 2 of U.S. Patent Application Publication ...				US Patent US9273043 (2016) BindingDB Entry DOI: 10.7270/Q2D7998G
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM210898 (US9273043, A126(e)) Show SMILES C[C@@H]1CN(CCN1C(=O)Nc1nc2ccc(C)cc2s1)c1ncc(cc1F)[C@@H](O)CO |r| Show InChI InChI=1S/C21H24FN5O3S/c1-12-3-4-16-18(7-12)31-20(24-16)25-21(30)27-6-5-26(10-13(27)2)19-15(22)8-14(9-23-19)17(29)11-28/h3-4,7-9,13,17,28-29H,5-6,10-11H2,1-2H3,(H,24,25,30)/t13-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18.2	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description One day prior to assay, TRPV1/CHO cells were seeded in 96-well clear-bottom black plates (20,000 cells/well) in growth media. On the day of the exper...				US Patent US9273043 (2016) BindingDB Entry DOI: 10.7270/Q2D7998G
					More data for this Ligand-Target Pair