BDBM213748 US9284299, PKF115-584::US9738628, Compound PKF115-584
SMILES: COc1cc(O)c2c3c1c1c(OC)cc(O)c4c1c(c(C[C@@H](C)OC(=O)c1ccccc1)c(OC)c4=O)c3c(C[C@@H](C)OC(=O)Oc1ccc(O)cc1)c(OC)c2=O
InChI Key: InChIKey=SRJYZPCBWDVSGO-NHCUHLMSSA-N
Data: 5 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-catenin/E-cadherin (Homo sapiens (Human)) | BDBM213748 (US9284299, PKF115-584 | US9738628, Compound PKF115...) | PDB GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 1.30E+4 | -6.66 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
University of Utah Research Foundation US Patent | Assay Description Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino... | US Patent US9284299 (2016) BindingDB Entry DOI: 10.7270/Q2WW7GGC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-catenin/Tcf4 (Homo sapiens (Human)) | BDBM213748 (US9284299, PKF115-584 | US9738628, Compound PKF115...) | PDB GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 1.78E+4 | -6.48 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
University of Utah Research Foundation US Patent | Assay Description Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino... | US Patent US9284299 (2016) BindingDB Entry DOI: 10.7270/Q2WW7GGC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-catenin (Homo sapiens (Human)) | BDBM213748 (US9284299, PKF115-584 | US9738628, Compound PKF115...) | PDB GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 1.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah Research Foundation US Patent | Assay Description Experiments were performed in white opaque 384-well plates from PerkinElmer (Waltham, Mass.), and the samples were read on a Synergy 2 plate reader (... | US Patent US9738628 (2017) BindingDB Entry DOI: 10.7270/Q27P91H7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-catenin (Homo sapiens (Human)) | BDBM213748 (US9284299, PKF115-584 | US9738628, Compound PKF115...) | PDB GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 1.78E+4 | -6.48 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
University of Utah Research Foundation US Patent | Assay Description Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino... | US Patent US9284299 (2016) BindingDB Entry DOI: 10.7270/Q2WW7GGC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-catenin/APC-R3 (Homo sapiens (Human)) | BDBM213748 (US9284299, PKF115-584 | US9738628, Compound PKF115...) | PDB GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 5.39E+4 | -5.82 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
University of Utah Research Foundation US Patent | Assay Description Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino... | US Patent US9284299 (2016) BindingDB Entry DOI: 10.7270/Q2WW7GGC | |||||||||||
More data for this Ligand-Target Pair |