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SMILES: CCOc1cc(C)ccc1OCCCOc1ccc2[C@H](CC(O)=O)CCc2c1

InChI Key: InChIKey=OKYICBFIEIXCLZ-SFHVURJKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 21773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM21773 (2-[(1S)-5-[3-(2-ethoxy-4-methylphenoxy)propoxy]-2,...) Show SMILES CCOc1cc(C)ccc1OCCCOc1ccc2[C@H](CC(O)=O)CCc2c1 |r| Show InChI InChI=1S/C23H28O5/c1-3-26-22-13-16(2)5-10-21(22)28-12-4-11-27-19-8-9-20-17(14-19)6-7-18(20)15-23(24)25/h5,8-10,13-14,18H,3-4,6-7,11-12,15H2,1-2H3,(H,24,25)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	7.4	22
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...				J Med Chem 50: 984-1000 (2007) Article DOI: 10.1021/jm061299k BindingDB Entry DOI: 10.7270/Q2NK3C93
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM21773 (2-[(1S)-5-[3-(2-ethoxy-4-methylphenoxy)propoxy]-2,...) Show SMILES CCOc1cc(C)ccc1OCCCOc1ccc2[C@H](CC(O)=O)CCc2c1 |r| Show InChI InChI=1S/C23H28O5/c1-3-26-22-13-16(2)5-10-21(22)28-12-4-11-27-19-8-9-20-17(14-19)6-7-18(20)15-23(24)25/h5,8-10,13-14,18H,3-4,6-7,11-12,15H2,1-2H3,(H,24,25)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.20	n/a	n/a	n/a	25
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...				J Med Chem 50: 984-1000 (2007) Article DOI: 10.1021/jm061299k BindingDB Entry DOI: 10.7270/Q2NK3C93
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM21773 (2-[(1S)-5-[3-(2-ethoxy-4-methylphenoxy)propoxy]-2,...) Show SMILES CCOc1cc(C)ccc1OCCCOc1ccc2[C@H](CC(O)=O)CCc2c1 |r| Show InChI InChI=1S/C23H28O5/c1-3-26-22-13-16(2)5-10-21(22)28-12-4-11-27-19-8-9-20-17(14-19)6-7-18(20)15-23(24)25/h5,8-10,13-14,18H,3-4,6-7,11-12,15H2,1-2H3,(H,24,25)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	8.13E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at Homo sapiens (human) PPARgamma expressed in mouse 3T3-L1 cells incubated for 2 days followed by compound wash out measured after ...				Citation and Details Article DOI: 10.1007/s00044-011-9599-z BindingDB Entry DOI: 10.7270/Q22J6FR8
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM21773 (2-[(1S)-5-[3-(2-ethoxy-4-methylphenoxy)propoxy]-2,...) Show SMILES CCOc1cc(C)ccc1OCCCOc1ccc2[C@H](CC(O)=O)CCc2c1 |r| Show InChI InChI=1S/C23H28O5/c1-3-26-22-13-16(2)5-10-21(22)28-12-4-11-27-19-8-9-20-17(14-19)6-7-18(20)15-23(24)25/h5,8-10,13-14,18H,3-4,6-7,11-12,15H2,1-2H3,(H,24,25)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	4.55E+8	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at GST-tagged Homo sapiens (human) PPARdelta ligand binding domain after 2 hr by FRET assay				Citation and Details Article DOI: 10.1007/s00044-011-9599-z BindingDB Entry DOI: 10.7270/Q22J6FR8
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM21773 (2-[(1S)-5-[3-(2-ethoxy-4-methylphenoxy)propoxy]-2,...) Show SMILES CCOc1cc(C)ccc1OCCCOc1ccc2[C@H](CC(O)=O)CCc2c1 |r| Show InChI InChI=1S/C23H28O5/c1-3-26-22-13-16(2)5-10-21(22)28-12-4-11-27-19-8-9-20-17(14-19)6-7-18(20)15-23(24)25/h5,8-10,13-14,18H,3-4,6-7,11-12,15H2,1-2H3,(H,24,25)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.24E+3	n/a	n/a	n/a	25
Bayer HealthCare Pharmaceuticals Corporation					Assay Description PPAR gamma activity was assessed by using the IRBA in mouse 3T3-L1 cells. This assay measures the ability of test compound to cause an increase in th...				J Med Chem 50: 984-1000 (2007) Article DOI: 10.1021/jm061299k BindingDB Entry DOI: 10.7270/Q2NK3C93
					More data for this Ligand-Target Pair