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SMILES: CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCSc12)c1ccccc1

InChI Key: InChIKey=IBBNYQVPCFRLPB-MAUKXSAKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM218534 (US9284333, 16ks | US9884860, Example 16ks) Show SMILES CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCSc12)c1ccccc1 |r| Show InChI InChI=1S/C22H27N3O2S/c1-3-18(16-9-5-4-6-10-16)23-20(26)17-14-19(25-12-13-28-22(17)25)21(27)24-11-7-8-15(24)2/h4-6,9-10,14-15,18H,3,7-8,11-13H2,1-2H3,(H,23,26)/t15-,18+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9884860 (2018) BindingDB Entry DOI: 10.7270/Q2862JGT
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM218534 (US9284333, 16ks | US9884860, Example 16ks) Show SMILES CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCSc12)c1ccccc1 |r| Show InChI InChI=1S/C22H27N3O2S/c1-3-18(16-9-5-4-6-10-16)23-20(26)17-14-19(25-12-13-28-22(17)25)21(27)24-11-7-8-15(24)2/h4-6,9-10,14-15,18H,3,7-8,11-13H2,1-2H3,(H,23,26)/t15-,18+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9284333 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2FMC
					More data for this Ligand-Target Pair