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BDBM218840 TATA-FXII618 (14)

SMILES: CSCCC(=O)N1CN(CN(C1)C(=O)CCSC)C(=O)CCSC

InChI Key: InChIKey=XNEWOOABUWKDES-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 218840   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor XII (FXII)


(Homo sapiens (Human))		BDBM218840
PNG
(TATA-FXII618 (14))
Show SMILES CSCCC(=O)N1CN(CN(C1)C(=O)CCSC)C(=O)CCSC
Show InChI InChI=1S/C15H27N3O3S3/c1-22-7-4-13(19)16-10-17(14(20)5-8-23-2)12-18(11-16)15(21)6-9-24-3/h4-12H2,1-3H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 25n/an/an/an/an/an/a7.4n/a



University of Glasgow



Assay Description
The inhibition of plasma kallikrein and coagulation factor FXII was assessed by incubating the proteases with bicyclic peptide (twofold dilutions) an...

Chembiochem 18: 387-395 (2017)


Article DOI: 10.1002/cbic.201600612
BindingDB Entry DOI: 10.7270/Q2H9942B
More data for this
Ligand-Target Pair