BDBM220898 US9302996, 13-3
SMILES: CC(C)(COc1ccc(cn1)-c1ccc(cn1)-c1nc(c[nH]1)C(F)(F)F)C(O)=O
InChI Key: InChIKey=KBYMCUBCOVUPIR-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human)) | BDBM220898 (US9302996, 13-3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | 7.4 | 30 |
MITSUBISHI TANABE PHARMA CORPORATION US Patent | Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w... | US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N | |||||||||||
More data for this Ligand-Target Pair |