BDBM220985 US9302996, 100-5

SMILES: Cc1cc(OCC2(CC2)C(O)=O)ncc1-c1ccc(-c2nc(c[nH]2)C(F)(F)F)c(Cl)c1

InChI Key: InChIKey=RQAJENVNEYDJLO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 220985   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM220985 (US9302996, 100-5) Show SMILES Cc1cc(OCC2(CC2)C(O)=O)ncc1-c1ccc(-c2nc(c[nH]2)C(F)(F)F)c(Cl)c1 Show InChI InChI=1S/C21H17ClF3N3O3/c1-11-6-17(31-10-20(4-5-20)19(29)30)26-8-14(11)12-2-3-13(15(22)7-12)18-27-9-16(28-18)21(23,24)25/h2-3,6-9H,4-5,10H2,1H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair