BDBM221022 US9302996, 137
SMILES: Cc1cc(OCC2(CCC2)C(O)=O)ncc1-c1cnc(-c2ncc([nH]2)C(F)(F)F)c(F)c1
InChI Key: InChIKey=WYYRKKQFJUHHJW-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human)) | BDBM221022 (US9302996, 137) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.4 | 30 |
MITSUBISHI TANABE PHARMA CORPORATION US Patent | Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w... | US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N | |||||||||||
More data for this Ligand-Target Pair |