BDBM222062 2-(4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)benzoyl)-N-(2-fluorophenyl)hydrazinecarbothioamide (3)

SMILES: Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)NNC(=S)Nc1ccccc1F

InChI Key: InChIKey=MTPKCSYFHWEBOB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222062   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
α-glucosidase (Saccharomyces cerevisiae S288c (Baker's yeast))	BDBM222062 (2-(4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)benzoy...) Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)NNC(=S)Nc1ccccc1F Show InChI InChI=1S/C23H20FN5OS/c1-13-11-19-20(12-14(13)2)26-21(25-19)15-7-9-16(10-8-15)22(30)28-29-23(31)27-18-6-4-3-5-17(18)24/h3-12H,1-2H3,(H,25,26)(H,28,30)(H2,27,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.31E+5	n/a	n/a	n/a	n/a	6.8	37
Universiti Teknologi MARA (UiTM)					Assay Description The enzyme inhibition was evaluated according to the method previously reported by Zawawi et al. [Zawawi et al., Bioorg. Chem., 23:3119] with slight ...				Bioorg Chem 70: 184-191 (2017) Article DOI: 10.1016/j.bioorg.2016.12.009 BindingDB Entry DOI: 10.7270/Q27P8X71
					More data for this Ligand-Target Pair