BDBM222063 2-(4-(5,6-Dimethyl-1H-benzo[d]imidazol-2-yl)benzoyl)-N-(2-methoxyphenyl)hydrazinecarbothioamide (4)

SMILES: COc1ccccc1NC(=S)NNC(=O)c1ccc(cc1)-c1nc2cc(C)c(C)cc2[nH]1

InChI Key: InChIKey=ZYEJVCZVTSLVSC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222063   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
α-glucosidase (Saccharomyces cerevisiae S288c (Baker's yeast))	BDBM222063 (2-(4-(5,6-Dimethyl-1H-benzo[d]imidazol-2-yl)benzoy...) Show SMILES COc1ccccc1NC(=S)NNC(=O)c1ccc(cc1)-c1nc2cc(C)c(C)cc2[nH]1 Show InChI InChI=1S/C24H23N5O2S/c1-14-12-19-20(13-15(14)2)26-22(25-19)16-8-10-17(11-9-16)23(30)28-29-24(32)27-18-6-4-5-7-21(18)31-3/h4-13H,1-3H3,(H,25,26)(H,28,30)(H2,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.46E+5	n/a	n/a	n/a	n/a	6.8	37
Universiti Teknologi MARA (UiTM)					Assay Description The enzyme inhibition was evaluated according to the method previously reported by Zawawi et al. [Zawawi et al., Bioorg. Chem., 23:3119] with slight ...				Bioorg Chem 70: 184-191 (2017) Article DOI: 10.1016/j.bioorg.2016.12.009 BindingDB Entry DOI: 10.7270/Q27P8X71
					More data for this Ligand-Target Pair