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BDBM222069 N-(4-bromophenyl)-2-(4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)benzoyl)hydrazinecarbothioamide (10)

SMILES: Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)NNC(=S)Nc1ccc(Br)cc1

InChI Key: InChIKey=XFUHLFZXIWLKEQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222069   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))		BDBM222069
PNG
(N-(4-bromophenyl)-2-(4-(5,6-dimethyl-1H-benzo[d]im...)
Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)NNC(=S)Nc1ccc(Br)cc1
Show InChI InChI=1S/C23H20BrN5OS/c1-13-11-19-20(12-14(13)2)27-21(26-19)15-3-5-16(6-4-15)22(30)28-29-23(31)25-18-9-7-17(24)8-10-18/h3-12H,1-2H3,(H,26,27)(H,28,30)(H2,25,29,31)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.06E+4n/an/an/an/a6.837



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Zawawi et al. [Zawawi et al., Bioorg. Chem., 23:3119] with slight ...

Bioorg Chem 70: 184-191 (2017)


Article DOI: 10.1016/j.bioorg.2016.12.009
BindingDB Entry DOI: 10.7270/Q27P8X71
More data for this
Ligand-Target Pair