BDBM222074 2-(4-(5,6-Dimethyl-1H-benzo[d]imidazol-2-yl)benzoyl)-N-(4(trifluoromethyl)phenyl)hydrazinecarbothioamide (15)

SMILES: Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)NNC(=S)Nc1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=LUFCEXBALIOURO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222074   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
α-glucosidase (Saccharomyces cerevisiae S288c (Baker's yeast))	BDBM222074 (2-(4-(5,6-Dimethyl-1H-benzo[d]imidazol-2-yl)benzoy...) Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)NNC(=S)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H20F3N5OS/c1-13-11-19-20(12-14(13)2)30-21(29-19)15-3-5-16(6-4-15)22(33)31-32-23(34)28-18-9-7-17(8-10-18)24(25,26)27/h3-12H,1-2H3,(H,29,30)(H,31,33)(H2,28,32,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.63E+5	n/a	n/a	n/a	n/a	6.8	37
Universiti Teknologi MARA (UiTM)					Assay Description The enzyme inhibition was evaluated according to the method previously reported by Zawawi et al. [Zawawi et al., Bioorg. Chem., 23:3119] with slight ...				Bioorg Chem 70: 184-191 (2017) Article DOI: 10.1016/j.bioorg.2016.12.009 BindingDB Entry DOI: 10.7270/Q27P8X71
					More data for this Ligand-Target Pair