BDBM222076 2-(4-(5,6-Dimethyl-1H-benzo[d]imidazol-2-yl)benzoyl)-N-(p-tolyl)hydrazinecarbothioamide (17)

SMILES: Cc1ccc(NC(=S)NNC(=O)c2ccc(cc2)-c2nc3cc(C)c(C)cc3[nH]2)cc1

InChI Key: InChIKey=SNZZDLNFBSLHII-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
α-glucosidase (Saccharomyces cerevisiae S288c (Baker's yeast))	BDBM222076 (2-(4-(5,6-Dimethyl-1H-benzo[d]imidazol-2-yl)benzoy...) Show SMILES Cc1ccc(NC(=S)NNC(=O)c2ccc(cc2)-c2nc3cc(C)c(C)cc3[nH]2)cc1 Show InChI InChI=1S/C24H23N5OS/c1-14-4-10-19(11-5-14)25-24(31)29-28-23(30)18-8-6-17(7-9-18)22-26-20-12-15(2)16(3)13-21(20)27-22/h4-13H,1-3H3,(H,26,27)(H,28,30)(H2,25,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.98E+5	n/a	n/a	n/a	n/a	6.8	37
Universiti Teknologi MARA (UiTM)					Assay Description The enzyme inhibition was evaluated according to the method previously reported by Zawawi et al. [Zawawi et al., Bioorg. Chem., 23:3119] with slight ...				Bioorg Chem 70: 184-191 (2017) Article DOI: 10.1016/j.bioorg.2016.12.009 BindingDB Entry DOI: 10.7270/Q27P8X71
					More data for this Ligand-Target Pair