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BDBM222352 IPR-1200 (5)

SMILES: Cc1ccc(cc1Br)N1C(C(C(=O)c2ccc(cc2)C(C)(C)C)=C(O)C1=O)c1cccc(F)c1

InChI Key: InChIKey=SJEZKWDVFIWVOS-UHFFFAOYSA-N

Data: 1 KI  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222352   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Urokinase receptor (uPAR)


(Homo sapiens (Human))		BDBM222352
PNG
(IPR-1200 (5))
Show SMILES Cc1ccc(cc1Br)N1C(C(C(=O)c2ccc(cc2)C(C)(C)C)=C(O)C1=O)c1cccc(F)c1 |t:24|
Show InChI InChI=1S/C28H25BrFNO3/c1-16-8-13-21(15-22(16)29)31-24(18-6-5-7-20(30)14-18)23(26(33)27(31)34)25(32)17-9-11-19(12-10-17)28(2,3)4/h5-15,24,33H,1-4H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 2.70E+3n/a 2.74E+4n/an/an/an/an/an/a



Indiana University School of Medicine



Assay Description
Polarized fluorescence intensities were measured using an EnVision Multilabel plate reader (PerkinElmer) with excitation and emission wavelengths of ...

Biochemistry 56: 1768-1784 (2017)


Article DOI: 10.1021/acs.biochem.6b01039
BindingDB Entry DOI: 10.7270/Q2NS0SQC
More data for this
Ligand-Target Pair