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BDBM222356 IPR-1185 (9)

SMILES: Cc1ccc(cc1Br)N1C(C(C(=O)c2ccc(Cl)cc2)=C(O)C1=O)c1ccc(F)nc1F

InChI Key: InChIKey=FHBOYHIJCUXWJS-UHFFFAOYSA-N

Data: 1 KI  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222356   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Urokinase receptor (uPAR)


(Homo sapiens (Human))		BDBM222356
PNG
(IPR-1185 (9))
Show SMILES Cc1ccc(cc1Br)N1C(C(C(=O)c2ccc(Cl)cc2)=C(O)C1=O)c1ccc(F)nc1F |t:21|
Show InChI InChI=1S/C23H14BrClF2N2O3/c1-11-2-7-14(10-16(11)24)29-19(15-8-9-17(26)28-22(15)27)18(21(31)23(29)32)20(30)12-3-5-13(25)6-4-12/h2-10,19,31H,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 1.70E+3n/a 3.56E+4n/an/an/an/an/an/a



Indiana University School of Medicine



Assay Description
Polarized fluorescence intensities were measured using an EnVision Multilabel plate reader (PerkinElmer) with excitation and emission wavelengths of ...

Biochemistry 56: 1768-1784 (2017)


Article DOI: 10.1021/acs.biochem.6b01039
BindingDB Entry DOI: 10.7270/Q2NS0SQC
More data for this
Ligand-Target Pair