BDBM222394 IPR-1154 (47)

SMILES: COC1=C(C(N(C1=O)c1ccc(C)c(Br)c1)c1cccc(F)c1)C(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=LNQLDUQTUULFOU-UHFFFAOYSA-N

Data: 1 KI

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222394   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase receptor (uPAR) (Homo sapiens (Human))	BDBM222394 (IPR-1154 (47)) Show SMILES COC1=C(C(N(C1=O)c1ccc(C)c(Br)c1)c1cccc(F)c1)C(=O)c1ccc(Cl)cc1 |t:2| Show InChI InChI=1S/C25H18BrClFNO3/c1-14-6-11-19(13-20(14)26)29-22(16-4-3-5-18(28)12-16)21(24(32-2)25(29)31)23(30)15-7-9-17(27)10-8-15/h3-13,22H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.35E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine					Assay Description Polarized fluorescence intensities were measured using an EnVision Multilabel plate reader (PerkinElmer) with excitation and emission wavelengths of ...				Biochemistry 56: 1768-1784 (2017) Article DOI: 10.1021/acs.biochem.6b01039 BindingDB Entry DOI: 10.7270/Q2NS0SQC
					More data for this Ligand-Target Pair