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SMILES: Clc1cccc(Cl)c1\C=N\NC(=O)N\N=C\c1c(Cl)cccc1Cl

InChI Key: InChIKey=WJMPEDBFVZXTPW-BPYXDGQXSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Bos taurus)	BDBM222435 (N'',N'''-Bis[(E)-(2,6-dichlorophenyl)methylide...) Show SMILES Clc1cccc(Cl)c1\C=N\NC(=O)N\N=C\c1c(Cl)cccc1Cl Show InChI InChI=1S/C15H10Cl4N4O/c16-11-3-1-4-12(17)9(11)7-20-22-15(24)23-21-8-10-13(18)5-2-6-14(10)19/h1-8H,(H2,22,23,24)/b20-7+,21-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
University of Karachi; Government College University Faisalabad					Assay Description Kinetic studies were performed by using different concentration of inhibitors over different concentrations of substrate (4-NPA) such as 0.175, 0.35,...				Bioorg Chem 72: 89-101 (2017) Article DOI: 10.1016/j.bioorg.2017.03.014 BindingDB Entry DOI: 10.7270/Q2125RHB
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Bos taurus)	BDBM222435 (N'',N'''-Bis[(E)-(2,6-dichlorophenyl)methylide...) Show SMILES Clc1cccc(Cl)c1\C=N\NC(=O)N\N=C\c1c(Cl)cccc1Cl Show InChI InChI=1S/C15H10Cl4N4O/c16-11-3-1-4-12(17)9(11)7-20-22-15(24)23-21-8-10-13(18)5-2-6-14(10)19/h1-8H,(H2,22,23,24)/b20-7+,21-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.46E+3	n/a	n/a	n/a	n/a	7.4	25
University of Karachi; Government College University Faisalabad					Assay Description In this assay, 4-nitrophenyl acetate (4-NPA), a colorless compound, was hydrolyzed to 4-nitrophenol and CO2. The reaction was followed by measuring t...				Bioorg Chem 72: 89-101 (2017) Article DOI: 10.1016/j.bioorg.2017.03.014 BindingDB Entry DOI: 10.7270/Q2125RHB
					More data for this Ligand-Target Pair