null
SMILES: Nc1nc([O-])c2ncn([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)C[P+](O)(O)[O-])[C@@H](O)[C@H]3O)c2n1
InChI Key: InChIKey=PHBDHXOBFUBCJD-KQYNXXCUSA-M
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Rattus norvegicus (Rat)) | BDBM223202 (β,γ-methyleneguanosine 5′-triphosp...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Waterloo | Assay Description The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE... | Biochemistry 56: 2106-2115 (2017) Article DOI: 10.1021/acs.biochem.7b00178 BindingDB Entry DOI: 10.7270/Q2D50KTV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] [H477R] (Rattus norvegicus (Rat)) | BDBM223202 (β,γ-methyleneguanosine 5′-triphosp...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6.96E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Waterloo | Assay Description The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE... | Biochemistry 56: 2106-2115 (2017) Article DOI: 10.1021/acs.biochem.7b00178 BindingDB Entry DOI: 10.7270/Q2D50KTV | |||||||||||
More data for this Ligand-Target Pair |